Antigenic Relationship Between H. Influenzae Type B and Pneumococcus Type VI.

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Abstract
(1) Certain anti-H. influenzæ horse serum reacts with SSS of pneumococcus type 6. Quantitatively, the precipitation reaction parallels that obtained with anti-pneumococcus type 6 serum. (2) SSS of pneumococcus type 6 absorbs the homologous antibodies, but does not affect the antibodies against the specific polysaccharide of H. influenzæ type b. (3) Absorption of the serum with the polysaccharide of the influenza bacillus removes both homologous antibodies and precipitins against the SSS of pneumococcus type 6. (4) It is concluded that such an anti-H. influenzæ horse serum contains two distinct antibodies and that some antigenic relationship exists between the available specific polysaccharide of H. influenzæ type b and the available SSS of pneumococcus type 6.

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