Anti-microbial activity of amniotic fluid β-lysin and the influence of zinc ion

Abstract
Summary Amniotic fluid β-lysin was found to have zinc-dependent bacteriostatic activity against the enteric bacilli, anaerobic Gram-negative bacilli and Gram-positive aerobic and anaerobic cocci. In contrast, β-lysin was found to exhibit bactericidal activity against the anaerobic and aerobic Gram-positive bacilli. This bactericidal activity was independent of zinc ion concentration. The clinical and biochemical implications of these observations are discussed.

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