Serum from Lps Nonresponder C3H/HeJ Mice Does Not Support the Formation of Functional Eac Reagents
Open Access
- 1 August 1978
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 121 (2) , 619-621
- https://doi.org/10.4049/jimmunol.121.2.619
Abstract
Serum from C3H/HeJ mice in contrast to serum from other mouse strains does not convert EA into EAC. A factor in supportive serum permits nonsupportive C3H/HeJ serum to produce a functional EAC-rosetting reagent. This factor is heat stable. Its concentration in serum parallels the sensitivity of mice to LPS. It is absent or inoperative when sensitivity is reduced on a genetic basis and increased when sensitivity is increased by treatment with BCG.This publication has 0 references indexed in Scilit: