Differentiated Rat Glial Cell Strain in Tissue Culture
- 26 July 1968
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 161 (3839) , 370-371
- https://doi.org/10.1126/science.161.3839.370
Abstract
Rat glial tumors, induced by injections of N-nitrosomethylurea, were plated and propagated in culture. Among a few cell strains obtained, one clone contains S-100 protein, which is unique to brain in vertebrates. Stationary-phase cultures contain approximately ten times more S-100 protein per cell than exponentially growing cells. When injected into newborn rats, cells producing S-100 grew as a glial tumor, which contained S-100 protein.This publication has 7 references indexed in Scilit:
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