Inhibition of Na-alanine contransport in oocytes ofXenopus laevis during meiotic maturation is voltage-regulated

Abstract
During progesterone-induced maturation of oocytes ofXenopus laevis the fast decrease of the rate of Na+-alanine cotransport is accompanied by a depolarization of the membrane potential and an increase in the intracellular Na+ activity. It is demonstrated that the decrease of the Na+-dependent alanine uptake is the result of the depolarization while the simultaneous increase in intracellular Na+ activity has no significant effect.