A progestagen-dependent endometrial protein in human amniotic fluid

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Abstract
A protein was detected in human amniotic fluid that had properties identical to those of the progestagen-dependent endometrial protein. The amniotic fluid protein concentration was maximal during wk 15-18 of pregnancy and then declined rapidly. The protein was not detected in immature and mature placentae, ovary, Fallopian tube, myometrium and cervix. Evidently a specific protein synthesized by the human uterine decidua is transported to the amniotic sac.