Bactericidal photoproducts in medium containing riboflavin plus aromatic compounds and MnCl2

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Abstract
Exposure to visible light of growth medium containing riboflavin and indole at low concentrations created photoproducts highly toxic to Salmonella typhimurium and other bacteria. No toxicity was detected in the dark or when either component was present singly. Other aromatic compounds (serotonin, indole-3-acetic acid, indole-3-propionic acid, tryptophan, tyrosine, phenylalanine and p-aminobenzoic acid) tested in plase of indole produced various degrees of toxicity. The presence of MnCl2 significantly enhanced the toxicity. Addition of catalase eliminated the toxicity, indicating an important role for H2O2.