Localized Reversible Frameshift Mutation in the flhA Gene Confers Phase Variability to Flagellin Gene Expression in Campylobacter coli
- 1 January 2000
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 182 (1) , 207-210
- https://doi.org/10.1128/jb.182.1.207-210.2000
Abstract
Phase variation of flagellin gene expression in Campylobacter coli UA585 was correlated with high-frequency, reversible insertion and deletion frameshift mutations in a short homopolymeric tract of thymine residues located in the N-terminal coding region of the flhA gene. Mutation-based phase variation inflhA may generate functional diversity in the host and environment.Keywords
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