The Effects of Actinomycin D on RNA Synthesis in Measles Virus-Infected Cells
- 1 February 1977
- journal article
- research article
- Published by Microbiology Society in Journal of General Virology
- Vol. 34 (2) , 391-396
- https://doi.org/10.1099/0022-1317-34-2-391
Abstract
The effects of actinomycin D on the production of genomic RNA, mRNA and protein in measles virus-infected [African green monkey kidney Vero] cells were investigated. Whereas high concentrations of the drug inhibited genome synthesis, the production of mRNA was unaffected and in some cases enhanced. These effects were shown, at least in part, to be due to a secondary effect of the drug which caused an inhibition of virus-specific protein synthesis.This publication has 0 references indexed in Scilit: