Possible adverse reactions to an enzyme‐containing washing powder

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Abstract
Following the launch of an enzyme (alcalase) containing washing powder, the manufactures received numerous complaints from domestic users suggesting that it was responsible either for the precipitation of a rash or the exacerbation of a pre-existing rash. The 255 individuals living in London postal districts who complained to the manufactures were contacted: 80 of them agreed to be investigated by patch and prick testing, and to a user test involving the double blind wearing of vests washed with the product. The results failed to substantiate that the enzyme containing washing powder was responsible for any dermatological problem.