LINKAGE BETWEEN A MARKER LOCUS AND A QUANTITATIVE TRAIT OF SIBS
- 1 January 1983
- journal article
- research article
- Vol. 35 (2) , 263-273
Abstract
Several variations of a method for detecting linkage between a marker locus and a quantitative trait in full sib families are presented along with computational details. All variations are based on contrasts within qualifying families of 3 or more sibs. The empirical powers of the various test statistics, evaluated by simulation, were very similar, and also similar to that of Smith. These single-generation tests are likely to be successful only for many families and relatively tight linkage.This publication has 2 references indexed in Scilit:
- Simplified formulas for detecting linkage with a quantitative characterAnnals of Human Genetics, 1980
- A non‐parametric test for linkage with a quantitative characterAnnals of Human Genetics, 1975