Studies on the Mechanism of Cyhexatin Resistance in the Twospotted Spider Mite, Tetranychus urticae (Acari: Tetranychidae)

Abstract
A 100-fold difference in toxicity was obtained when cyhexatin was tested with a slide-dip method on a laboratory-pressured cyhexatin-resistant (ShJp) and susceptible (S) strain of twospotted spider mite, Tetranychus urticae Koch. No difference in penetration or metabolism of cyhexatin was observed between the two strains of mites. A 6.5-fold difference in cyhexatin inhibition of oligomycin-sensitive (OS) Mg2+ ATPase activity was found between the two strains of mites. An altered target site appears to be responsible in part for cyhexatin resistance.

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