Isoelectric focusing of rare transferrin (Tf) variants and common TfC subtypes

1 January 1979

journal article
research article
Published by Springer Nature in Human Genetics

Vol. 46 (1) , 83-87
https://doi.org/10.1007/bf00278905

Abstract

Transferrin^C (Tf^C) subtypes were determined by isoelectric focusing (PAGIF) on samples from 90 carriers of the Tf^B and Tf^D alleles. In all cases of CB and CD heterozygotes only one of the two common subtypes of the Tf^C allele, Tf^C1 or Tf^C2, was observed. This is considered strong support for the hypothesis of two common alleles at the Tf locus. The different isofocusing patterns of rare B and D variants are compared with the results obtained after agarose gel electrophoresis (AGE).

Keywords

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