Synthesis of maytansinoids: synthesis of an intermediate from D-glucose for the construction of maytansine

15 April 1980

journal article
Published by Canadian Science Publishing in Canadian Journal of Chemistry

Vol. 58 (8) , 858-860
https://doi.org/10.1139/v80-133

Abstract

D-Glucose was converted to the lactone 1, an intermediate containing the appropriate functionalities and correct stereochemistry for the construction of maytansine.

Keywords

LACTONE
CONVERTED
MAYTANSINOIDS
MAYTANSINE
CORRECT STEREOCHEMISTRY
INTERMEDIATE CONTAINING
APPROPRIATE FUNCTIONALITIES

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