Isolation and primary structure of bombyxin-IV, a novel molecular species of bombyxin from the silkworm, Bombyx mori.
- 1 January 1988
- journal article
- Published by Oxford University Press (OUP) in Agricultural and Biological Chemistry
- Vol. 52 (12) , 3035-3041
- https://doi.org/10.1271/bbb1961.52.3035
Abstract
From 1.2 × 106male adult heads of the silkworm, Bombyx mori, 0.16mg of bombyxin-IV was isolated, which was a novel molecular species of bombyxin, previously called 4K-prothoracicotropic hormone. Injection of 0.1 ng of bombyxin-IV into a dauer pupa of the Eri-silkworm, Samia cynthia ricini, evoked adult development. Microsequencing, chemical modification, enzymatic digestion, and fast atom bombardment mass spectrometry showed that bombyxin-IV consisted of two heterogeneous peptides linked by disulfide bonds and had a considerable sequence homology (62.5%) with bombyxin-II.Keywords
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