Artemisinin: current status
- 1 June 1994
- journal article
- Published by Oxford University Press (OUP) in Transactions of the Royal Society of Tropical Medicine and Hygiene
- Vol. 88, 3-4
- https://doi.org/10.1016/0035-9203(94)90459-6
Abstract
The compounds derived from the Chinese medicinal plant qinghao (Artemisia annua) are the most rapidly acting of all antimalarial drugs. They are effective when given parenterally, orally or by suppository. No serious adverse effect has yet been reported in humans. The artemisinin derivatives already have an established role in the treatment of multi-drug resistant falciparum malaria, but their wider use will depend on the results of current mortality and toxicity studies.Keywords
This publication has 16 references indexed in Scilit:
- Neurotoxicity in animals due to arteether and artemetherTransactions of the Royal Society of Tropical Medicine and Hygiene, 1994
- Single day mefloquine-artesunate combination in the treatment of multi-drug resistant falciparum malariaTransactions of the Royal Society of Tropical Medicine and Hygiene, 1994
- Rapid coma resolution with artemether in Malawian children with cerebral malariaThe Lancet, 1993
- QinghaosuThe Lancet, 1993
- Comparison of oral artemether and mefloquine in acute uncomplicated falciparum malariaThe Lancet, 1992
- An open randomized comparison of intravenous and intramuscular artesunate in severe falciparum malariaTransactions of the Royal Society of Tropical Medicine and Hygiene, 1992
- Randomised trial of artesunate and mefloquine alone and in sequence for acute uncomplicated falciparum malariaThe Lancet, 1992
- Comparative effectiveness of artemisinin suppositories and oral quinine in children with acute falciparum malariaTransactions of the Royal Society of Tropical Medicine and Hygiene, 1991
- A randomized comparative study of artemisinine (qinghaosu) suppositories and oral quinine in acute falciparum malariaTransactions of the Royal Society of Tropical Medicine and Hygiene, 1990
- The effect of mefloquine-artemether compared with quinine on patients with complicated falciparum malariaTransactions of the Royal Society of Tropical Medicine and Hygiene, 1988