Amphotericin B: Is a Lipid‐Formulation Gold Standard Feasible?

Abstract
Sir—We read with interest the article by Ostrosky-Zeichner et al. [1] proposing that lipid-based formulations of amphotericin B (LFABs) replace amphotericin B deoxycholate (AmBD) as the gold standard for treatment of most invasive mycoses. On the basis of a review of comparative efficacy, toxicity, and cost, we believe AmBD remains a viable first-line agent.