Arterial Pressure Changes in Experimental Renal Hypertensive Dogs Following Production of Femoral Arteriovenous Fistula

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Abstract
Production of a femoral arteriovenous fistula in dogs with experimental renal hypertension, produced either by controlled abdominal aortic constriction or by mild left renal artery constriction, results in a fall in mean arterial pressure to normotension or to near normotensive values. This hypotensive effect is unaccompanied by an increase in arterial pulse pressure. It is suggested that the antihypertensive effect of fistula production in such dogs is due to an increase in intrarenal volume pulsation.