Reproduction and Lactation in Highly Inbred Strains of Mice on Synthetic Diets

Abstract
Reproduction and lactation has been studied in highly inbred strains of mice fed purified diets. A diet containing vitamins A, D and E as well as thiamine, riboflavin, nicotinic acid, pantothenic acid, pyridoxine, choline, inositol and p-aminobenzoic acid was utterly inadequate for this purpose. The problem appears to be one of lactation. Addition of folic acid and folic acid plus biotin gave some success. Addition of biotin, folic acid, cystine and vitamin K gave much better results.

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