Piper methysticum: Enantiomeric Separation of Kavapyrones by High Performance Liquid Chromatography*
- 1 February 1997
- journal article
- research article
- Published by Georg Thieme Verlag KG in Planta Medica
- Vol. 63 (01) , 63-65
- https://doi.org/10.1055/s-2006-957606
Abstract
A simultaneous separation of the enantiomers of kawain, dihydrokawain, methysticin, and dihydromethysticin as well as the achiral dienolides yangonin and demethoxyyangonin was carried out on a ChiraSpher® NT column. This HPLC method can be used for the investigation of the enantiomeric purity of plant material and herbal medicines. The influence of temperature and flow rate are discussed in respect to the chromatographic resolution of the enantiomers. All tested enolide racemates can be preparatively separated on ChiraSpher® NT.Keywords
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