NEURO-BLASTOMA IN ADULTS - PATHOLOGIC FINDINGS AND CLINICAL OUTCOME

Google Scholar
  • 1 January 1985
    • journal article
    • research article
    • Vol. 109  (4) , 352-356
Abstract
Neuroblastoma in adults is uncommon. Adult patients with neuroblastoma have a better prognosis than children with these tumors. The clinical features of 8 adults with neuroblastoma were examined and related to tumor histopathology and immunohistochemistry using an antibody to neuron-specific enolase. When children and adults with neuroblastoma are compared by stage, adults do not have a better prognosis. Adults tend to have a different anatomic distribution of primary tumor sites, with more frequent extra-abdominal sites than are seen in children. Neuroblastomas arising in adults are similar to those seen in children by containing neuron-specific enolase, an enzyme associated with cells of neuroectodermal origin. Adult neuroblastomas are similar to their childhood counterparts in clinical behavior and pathologic features.

This publication has 4 references indexed in Scilit: