Long-term Stability of Albumin, Protein HC, Immunoglobulin G, κ- and λ-chain-immunoreactivity, Orosomucoid and α1-antitrypsin in Urine Stored at -20°C
- 1 January 1997
- journal article
- research article
- Published by Taylor & Francis in Scandinavian Journal of Urology and Nephrology
- Vol. 31 (1) , 67-71
- https://doi.org/10.3109/00365599709070305
Abstract
The stability of albumin, protein HC, immunoglobulin G, κ- and λ-chain immunoreactivity, orosomucoid and α1 -antitrypsin in urine stored at -20°C for up to 24 months was investigated. Significant decreases of the median concentration values for protein HC, IgG and α1-antitrypsin were observed for native urine. Addition to urine of a preservative solution containing benzamidinium chloride, EDTA, tris(hydroxymethyl)-aminomethane and azide prevented the decreases of the concentration values for protein HC and IgG but not for α1-antitrypsin. The median concentration values for albumin, orosomucoid and κ-and λ-chain immunoreactivity did not change significantly upon storage of native urine, nor for urine with the preservative solution.Keywords
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