ULTRASTRUCTURAL MORPHOMETRIC INVESTIGATIONS ON NORMAL HUMAN LIVER BIOPSIES

  • 1 January 1978
    • journal article
    • research article
    • Vol. 25  (2) , 119-123
Abstract
Normal liver biopsies of 14 volunteers were investigated using ultrastructural morphometry. Besides the determination of morphometric baseline data for comparative purposes particular emphasis was placed on the question, if morphometric evaluations of human livers yield reliable results despite a higher range of distribution than in experimental liver material. The surface of the smooth endoplasmic reticulum of human liver is significantly greater than the surface of rough endoplasmic reticulum. The morphometric data of the human liver tissue did not differ essentially from the values of the laboratory rat. The variance of the mean evaluated from the data of the 14 liver biopsies indicated that the SE of nearly all proved parameters was < 10% of the mean. Ultrastructural morphometric evaluations of human liver biopsy samples yield reliable results provided the samples investigated are sufficiently extensive.

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