MBK neuropathy among spray painters

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Abstract
The solvent methyl N-butyl ketone (MBK) may cause peripheral neuropathy in humans. An investigation was undertaken after 2 cases of peripheral neuropathy among spray painters at 1 work site were reported to the National Institute for Occupational Safety and Health [USA]. Twenty-six painters were interviewed and examined. Two had definite peripheral neuropathy and one had a probable case. Although one of these men had been exposed to Pb in the past, there are strong reasons to believe that MBK was responsible for his neuropathy. There was nothing to suggest excessive Pb absorption in the other 2 men.

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