Effect of continuous illumination on secretion of pregnane compounds by the rat ovary

Abstract
Differences in the secretion of pregnance compounds from rats with follicular polycystic ovaries under constant light and with normal preovulatory ovaries under light-dark conditions were compared. The injection of LH greatly increased the secretion of progesterone. 5α-pregnane-3,20-dione and 3α-hydroxy-5α-pregnan-20-one, in both types of ovaries, but the response of the two progesterone metabolites in the polycystic ovaries was low, suggesting low 5α-reductase activity.