Rheumatoid synovial cells in culture produce a growth inhibitor.
Open Access
- 1 April 1978
- journal article
- research article
- Published by Elsevier in Annals of the Rheumatic Diseases
- Vol. 37 (2) , 187-189
- https://doi.org/10.1136/ard.37.2.187
Abstract
Cultures of synovial cells obtained at surgery from patients with rheumatoid arthritis produced a protein which inhibits the mitosis of normal rabbit and human synovial cells, and of human lung fibroblasts. This mitotic inhibitory effect can be transferred to rabbit synovial cells by intra-articular injection of the animals with rheumatoid synovial cell cultures.This publication has 8 references indexed in Scilit:
- Rubella and Rheumatoid Arthritis: Hyaluronic Acid and Susceptibility of Cultured Rheumatoid Synovial Cells to VirusesExperimental Biology and Medicine, 1975
- Effect of cell-bound hyaluronic acid on infectivity of Newcastle disease virus for human synovial cells in vitro.Annals of the Rheumatic Diseases, 1974
- Virus resistance transferred from human rheumatoid cells to rabbit synovial cells. I. Methods and results of intra-articular injection of human cells into rabbit joints.Annals of the Rheumatic Diseases, 1974
- PROPERTIES OF SYNOVIAL CELLS IN CULTUREThe Journal of Experimental Medicine, 1971
- Connective Tissue Activation. II. Abnormalities of Cultured Rheumatoid Synovial CellsArthritis & Rheumatism, 1971
- Significance of persistent differences between normal and rheumatoid synovial membrane cells in cultureArthritis & Rheumatism, 1969
- Human Fibroblasts Infected with Rubella Virus Produce a Growth InhibitorScience, 1967