ASP1 (BACE2) Cleaves the Amyloid Precursor Protein at the β-Secretase Site
- 1 November 2000
- journal article
- Published by Elsevier in Molecular and Cellular Neuroscience
- Vol. 16 (5) , 609-619
- https://doi.org/10.1006/mcne.2000.0884
Abstract
No abstract availableKeywords
This publication has 33 references indexed in Scilit:
- Expression Analysis of BACE2 in Brain and Peripheral TissuesJournal of Biological Chemistry, 2000
- The gene encoding DRAP (BACE2), a glycosylated transmembrane protein of the aspartic protease family, maps to the Down critical regionFEBS Letters, 2000
- Identification of a Novel Aspartic Protease (Asp 2) as β-SecretaseMolecular and Cellular Neuroscience, 1999
- The Swedish mutation causes early-onset Alzheimer's disease by β-secretase cleavage within the secretory pathwayNature Medicine, 1995
- Selective neurotoxicity of COOH-terminal fragments of the β-amyloid precursor proteinNeuroscience Letters, 1993
- Release of Excess Amyloid β Protein from a Mutant Amyloid β Protein PrecursorScience, 1993
- Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein productionNature, 1992
- Targeting of cell-surface β-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragmentsNature, 1992
- Cleavage of Amyloid β Peptide During Constitutive Processing of Its PrecursorScience, 1990
- Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid proteinBiochemical and Biophysical Research Communications, 1984