Protective Effects of Misoprostol on Carbon Tetrachloride-Induced Liver Damage in the Rat

1 January 1991

journal article
Published by S. Karger AG in Pharmacology

Vol. 42 (5) , 283-286
https://doi.org/10.1159/000138809

Abstract

Effects of misoprostol on histologic and biochemical alterations caused by CCl4 were investigated in the rat. Misoprostol protected against CCl4-induced liver injury. A close correlation occurred between biochemical data and morphological changes. This hepatoprotective effect was observed only when misoprostol was given 30 min before CCl4.

Keywords

INDUCED LIVER
RAT
MORPHOLOGICAL
HEPATOPROTECTIVE
CCL4
PROTECTIVE EFFECTS
TETRACHLORIDE
EFFECTS OF MISOPROSTOL

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