Detrimental effect of left varicocele on the reproductive capacity of the early haploid male gamete.

  • 1 July 1996
    • journal article
    • Vol. 156  (1) , 267-70
Abstract
We evaluated the fertilizing capacity of round spermatids recovered from varicocelized rabbits. A left varicocele model was created in 5 rabbits (Group A). Four rabbits underwent a sham operation (Group B). After 3 months round spermatid nuclei were collected from the left testicle of each rabbit and injected into oocytes. Oocytes were cultured for 24 hours. The proportion of 2- to 4-cell stage embryos to the successfully injected oocytes was significantly lower in group A than in group B (p < 0.05). Our findings indicate a detrimental effect of varicocele on the fertilizing potential of round spermatid.

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