A COMPARATIVE STUDY OF RED CELL VOLUMES IN HUMAN SUBJECTS WITH RADIOACTIVE PHOSPHORUS TAGGED RED CELLS AND T-1824 DYE 12

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Abstract
The authors present a comparative study of red cell volumes in human subjects using T-1824 dye and radioactive P-tagged red cells. The 2 detns. were performed simultaneously on 38 subjects taken from the surgical services of the Medical College of Virginia Hospitals. Plasma dye concns. were measured on a Coleman Junior Spectrophotometer and radioactivity detns. were performed on hemolized red cells using a Geiger counter. They found that the red cell vol. by P32 was 20% less than by T-1824 plasma dye and hematocrit. The mean ratio of Bed cell volume by P32 Q 80 when th hematocrits were Red cell volume by T-1824 uncorrected and 0.87 when hemaiocrits were corrected by a factor 0.96. This difference is attributed to a difference of the hematocrit in peripheral veins and blood in other vessels of the body and to an intrinsic error in the centrifuge hematocrit. The results were in agreement with similar studies of red cell volumes using radio Fe.
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