Effect of Low, Normal and High Dietary Protein Intake on Urinary Amino Acid Excretion and Plasma Aminogram in Children

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Abstract
The influence of dietary protein intake on the urinary amino acid excretion, the plasma amino acid concentrations and the renal clearance of amino acids was studied in 14 children fed a low (LPD), a normal (NPD), and a high protein diet (HPD). A significant decrease in the quantitative urinary excretion of most amino acids was observed when the children were fed LPD instead of NPD, while no changes in the quantitative urinary amino acid excretion were seen when NPD and HPD were compared. No significant decrease in the plasma amino acid concentrations was seen when the protein intake was changed from NPD to LPD, while a significant increase in several amino acids was seen when HPD replaced NPD. The renal clearance of amino acids when on LPD, NPD and HPD, were compared in 11 children. On LPD, the renal clearances of many amino acids were low when compared with NPD but there were no changes in the renal clearances when HPD was given instead of NPD. The quantitative urinary amino acid excretions and plasma amino acid concentrations at a normal protein intake are presented as well.
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