On Antigens: Antigenic Properties of Glue, Wheat, and House Dust

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Abstract
Le Page Glue as an Antigen. In a previous communication, the results of detailed studies of the egg white and pollen antigens were presented (1). By means of the intravenous and Dale methods of testing for anaphylaxis, it was found that timothy and ragweed pollens were relatively poor anaphylactogens for the guinea pig. This characteristic could not be attributed to a quantitative factor, that is, dearth of pollen protein, for reasons described in detail, but could be shown to depend upon a qualitative difference in the antigenic principle in pollens. A study of the antigenic properties of glue was deemed of interest at that time, because of the fact that this antigen, like pollen, had been found to be extremely potent as an atopen in man (2), though previous attempts to sensitize animals with it had met with little success (3). These investigations have only recently been completed, and the results are herewith presented.

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