Pseudoxanthoma Elasticum and Mitral-Valve Prolapse
- 2 December 1982
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 307 (23) , 1451-1452
- https://doi.org/10.1056/nejm198212023072315
Abstract
To the Editor: Lebwohl and colleagues1 performed M-mode echocardiography on 14 patients affected by pseudoxanthoma elasticum and found mitral-valve prolapse in 11 (71 per cent) (July 22 issue). We are conducting a multidisciplinary assessment of pseudoxanthoma elasticum. Preliminary results (unpublished) of cardiologic examinations in 28 unrelated patients do not confirm this high prevalence of mitral-valve prolapse. None of the 17 women or 11 men (mean age, 43.3 years; range, 13 to 71 years) hada systolic click, and only one had an apical systolic murmur. M-mode echocardiograms in 16 patients showed mitral-valve prolapse in 1. Two-dimensional echocardiograms in 26 patients . . .Keywords
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