Determination of Halogenated Contaminants in Human Adipose Tissue
- 1 May 1986
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of AOAC INTERNATIONAL
- Vol. 69 (3) , 451-458
- https://doi.org/10.1093/jaoac/69.3.451
Abstract
<A method has been developed for determination of organochlorine contaminants in human adipose tissue. After fat extraction from the tissue with acetone-hexane (15 + 85, v/v), organochlorines were fractionated from fat by gel permeation chromatography with methylene chloride-cyclohexane (1 + 1, v/v) as solvent. After Florisil column cleanup, the GPC extract was analyzed by capillary column gas chromatography using 2 columns of different polarity. Compound identity was confirmed by gas chromatography-mass spectrometry using selected ion monitoring. Recoveries for fortification levels of 10-500 ng/g were greater than 80 % except for trichlorobenzene and hexachlorobutadiene (ca 60%).This publication has 4 references indexed in Scilit:
- Multiresidue Gas Chromatographic Method for Determining Organochlorine Pesticides in Poultry Fat: Collaborative StudyJournal of AOAC INTERNATIONAL, 1984
- A comparison of organochlorine residues in human adipose tissue autopsy samples from two Ontario municipalitiesJournal of Toxicology and Environmental Health, 1984
- Evaluation of Gel Permeation Chromatography for Clean up of Human Adipose Tissue Samples for GC/MS Analysis of Pesticides and Other ChemicalsJournal of Analytical Toxicology, 1981
- The Identification of Polychlorinated Terphenyls at Trace Levels in Human Adipose Tissue by Gas Chromatography/Mass SpectrometryJournal of Analytical Toxicology, 1978