QUANTITATIVE ASPECTS ON MITOCHONDRIAL MONOAMINE-OXIDASE IN HUMAN PLATELETS
- 1 January 1976
- journal article
- research article
- Vol. 54 (2) , 137-141
Abstract
The number of monoamine oxidase [MAO] molecules in human blood platelets was estimated by titration with the irreversible MAO inhibitor, pargyline, to be about 900/thrombocyte and 200-300/thrombocyte mitochondrion. MAO probably constitutes about 1/5000 of the platelet mitochondrial outer membrane surface. Molecular turnover numbers for benzylamine and tyramine were estimated at about 1470 and 720, respectively.This publication has 5 references indexed in Scilit:
- Additional evidence for the existence of several forms of mitochondrial monoamine oxidase in the mouseBiochemical Pharmacology, 1968
- The Purification of Pig Brain Mitochondrial Monoamine OxidaseEuropean Journal of Biochemistry, 1968
- Biogenic Amines and EmotionScience, 1967
- MITOCHONDRIAL MONOAMINE OXIDASE .I. PURIFICATION AND CHARACTERIZATION OF BOVINE KIDNEY ENZYME1967
- INTRACELLULAR DISTRIBUTION OF MONOAMINE OXIDASE 5-HYDROXYTRYPTAMINE AND HISTAMINE IN BLOOD PLATELETS OF RABBIT1966