The Distribution of Cholinesterases in Cats and Changes Caused by Hypophysectomy, Adrenalectomy, Undernutrition and DOCA.
- 1 April 1956
- journal article
- Published by Wiley in Acta Physiologica Scandinavica
- Vol. 37 (2-3) , 158-176
- https://doi.org/10.1111/j.1748-1716.1956.tb01352.x
Abstract
Summary.: 1. The cholinesterase activity of the “true” and “pseudo” types of homogenized submaxillary gland, gastro‐intestinal mucosa and liver was determined in five groups of cats: 1) normal, 2) hypophysectomized, 3) adrenalectomized, 4) adrenalectomized maintained on DOCA, 5) undernourished.2. In normal cats the choliiiesterase of the submaxillary gland is predominantly of the “true” type, in the liver the “pseudo” type only could be found, in the gastric mucosa the “pseudo” type prevails beside merely detectable amounts of “true” esterasc. while the mucosa of the small intestine is abundant in both types of esterase.3. Hypophysectomy and adrenalectomy are followed by a coilsiderable increase in the concentrations of “true” and “pseudo” cholinesterase in the salivary gland. Similar changes occur in the intestinal mucosa after adrenalectomy, while they are absent in the liver and gastric mucosa.4. In adrenalectomized cats treatment with DOCA possibly had a slight (statistically not significant) effect in lowering the cholinesterase levels of the salivary gland towards normal, while no such effect was observed in the intestinal mucosa.5. In cats on reduced food a decrease in both types of esterase activity was found in the mucosa of the small intestine, whereas in the salivary gland, gastric mucosa and liver no changes were detectable.Keywords
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