Skinned smooth muscle: calcium-calmodulin activation independent of myosin phosphorylation
- 1 November 1986
- journal article
- research article
- Published by Springer Nature in Pflügers Archiv - European Journal of Physiology
- Vol. 407 (5) , 569-571
- https://doi.org/10.1007/bf00657520
Abstract
In chemically skinned chicken gizzard smooth muscle fibers investigated shortly after preparation, a contraction may be induced by calcium and calmodulin which is independent of myosin phosphorylation at intermediate Ca2+-concentrations. However, fibers stored for a prolonged period also contract in the absence of exogenous calmodulin and exhibit a close relationship between force development and myosin phosphorylation.Keywords
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