Alprazolam Dependency: Use of Clonazepam for Withdrawal

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Abstract
Ten alprazolam-dependent patients were studied with clinical and biologic variables after equal doses of clonazepam were substituted for alprazolam. Withdrawal was accomplished over a seven-day period. Anxiety and plasma cortisol levels were measured and found not to be significantly different between the withdrawal period and the postwithdrawal medication-free period.

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