Analysis of hepatitis virus dna in the liver and serum of hbe antigen positive chimpanzee carriers
- 1 January 1982
- journal article
- research article
- Published by Wiley in Journal of Medical Virology
- Vol. 9 (3) , 189-199
- https://doi.org/10.1002/jmv.1890090306
Abstract
Hepatitis B viral DNA present in the liver of HBe antigen positive chimpanzee carriers is in the form of free viral molecules (3.2 Kb) and no integration into host DNA was observed. The 3.2 Kb form was not detected in the serum. Other discrete HBV DNA species with faster mobilities than the major 3.2 Kb were consistently detected both in the liver and in the serum and their possible significance is discussed.Keywords
This publication has 19 references indexed in Scilit:
- Integration of Hepatitis B Virus DNA into the Genome of Liver Cells in Chronic Liver Disease and Hepatocellular CarcinomaNew England Journal of Medicine, 1981
- State of hepatitis B virus DNA in hepatocytes of patients with hepatitis B surface antigen-positive and -negative liver diseases.Proceedings of the National Academy of Sciences, 1981
- Adenine arabinoside therapy in HBsAg-positive chronic liver disease: A controlled studyGastroenterology, 1981
- Identification of integrated hepatitis B virus DNA sequences in human hepatocellular carcinomasHepatology, 1981
- Integration of hepatitis B virus sequences and their expression in a human hepatoma cellNature, 1980
- Presence of integrated hepatitis B virus DNA sequences in cellular DNA of human hepatocellular carcinomaNature, 1980
- Identification of integrated hepatitis B virus DNA and expression of viral RNA in an HBsAg-producing human hepatocellular carcinoma cell lineNature, 1980
- A virus in Beechey ground squirrels that is related to hepatitis B virus of humans.Proceedings of the National Academy of Sciences, 1980
- Enhanced autoradiographic detection of 32P and 125I using intensifying screens and hypersensitized filmFEBS Letters, 1977
- Molecular analysis of the histone gene cluster of Psammechinus miliaris: II. The arrangement of the five histone-coding and spacer sequencesCell, 1976