THE ELECTROCARDIOGRAM IN FRIEDREICH DISEASE

Abstract
In 38 cases of Friedreich disease, the electrocardiogram was studied. In only one patient did clinical examination show a cardiac abnormality (complete heart block, Stokes-Adams syndrome, and premature systoles). In 12 patients the electrocardiogram was significantly altered. There were slight changes in another 10; the records were normal in the remaining patients. In 1 case there was complete heart block; in 6, the ECGs showed evidences of coronary disease; in 5 the T waves were low or inverted in the limb leads; there were various other changes in the remaining patients. It was found that patients showing absence of the tendon reflexes and extensor responses of the plantar reflexes were the ones more commonly showing changes in the electrocardiogram. Other neurological signs were more widespread in patients with the more conspicuous electrocardiographic changes.

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