HLA-A1, B8-Phenotype Association and HBs Antigenemia Evolution in 440 Hemodialyzed Patients

Abstract
HBs antigen (HBsAg) has been followed up every month in 440 hemodialyzed patients, typed for 26 HLA alleles of the A and B loci. An abnormally high rate of the HLA-A1, B8 association (18.6 %) was found in the group of patients able to eliminate HBsAg, when compared with the normal French population (5.05 %, p -4), and with the group of patients unable to eliminate HBsAg (7.0 %, p