Identification of a human T lymphocyte surface protein associated with the E-rosette receptor.

Open Access
Publisher Website
Google Scholar
Abstract
A new monoclonal murine antibody reacts with a 50,000 MW polypeptide that appears to be present on all E[erythrocyte]-rosetting cells is described. Evidently this antigen is either identical to or closely associated with the E receptor because of the high degree of concordance between E-rosette formation and 9.6 antigen expression; the inhibition of rosette formation by preincubation of cells with 9.6 antibody; and the observed failure of cells lysostripped of 9.6 antigen to form E-rosettes. This suggests cocapping of 9.6 antigen and the E receptor.