Introduction Franceschetti1 has recently introduced the term "fundus flavimaculatus" to describe a group of cases with multiple yellow or yellow-white areas in the retina identical to what is seen in some of the tapetoretinal degenerations, but in which the diagnosis of a tapetoretinal degeneration is not borne out by electrophysiologic and psychophysical tests. During the past year, five patients, similar in many respects to those reported by Franceschetti, have been seen at the National Institutes of Health, all referred with the diagnosis of tapetoretinal degeneration and associated macular degeneration. It is the purpose of this paper to report the findings in these patients and to emphasize the importance of physiologic testing as a guide to diagnosis, prognosis and genetic counseling. Methods All patients had complete ophthalmologic examinations as well as psychophysical and electrophysiologic studies. 1. Visual Fields. —Central visual fields were examined on the tangent screen with 1/1,000 and