A high incidence of megaloblastic anaemia, approximately three times that in white persons, has been found in Indian immigrants in Britain. The clinical, haematological, and biochemical features of 25 patients are described. All but one of these were living in the Southall area of Middlesex. In 15 cases the presenting haemoglobin was less than 7 g/100 ml and three of these were teenage girls. The majority (17 cases) were nutritional anaemias; the type of deficiency was variable and this group included some patients with vitamin B18 deficiency, some with folic acid deficiency, and some with deficiency of both vitamins. Among the remaining eight patients there were cases of pernicious anaemia, tropical sprue, gluten enteropathy, post-gastrectomy anaemia, and unexplained vitamin Bla malabsorption. Some of these conditions have previously been considered uncommon in Asiatic Indians.