Studies on Phosphorylation by Phosphoroguanidinates. The Mechanism of Action of Creatine: ATP Transphosphorylase (Creatine Kinase)

1 November 1971

journal article
Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences

Vol. 68 (11) , 2691-2693
https://doi.org/10.1073/pnas.68.11.2691

Abstract

The solvolyses of phosphorocreatine (creatine phosphate) and models for phosphorocreatine have been investigated and the results are applied to the mechanism of action of creatine kinase (EC 2.7.3.2). A metaphosphate intermediate appears to be involved.

Keywords

PHOSPHORYLATION
MODELS
PHOSPHOROGUANIDINATES
TRANSPHOSPHORYLASE
METAPHOSPHATE
ATP
SOLVOLYSES
PHOSPHOROCREATINE

This publication has 2 references indexed in Scilit:

Aspects of Enzyme Mechanisms Studied by Nuclear Spin Relaxation Induced by Paramagnetic Probes
Published by Wiley ,1970
STUDIES ON PHOSPHORYLATION .25. METAL ION CATALYSED REACTIONS OF PHOSPHAGENS
1963