Site of Prenylation Reaction in Synthesis of Phylloquinone (Vitamin K1) by Spinach Chloroplasts

Abstract
In spinach chloroplasts, 1,4‐dihydroxy‐2‐naphthoate is prenylated by phytyldiphosphate and subsequently methylated by S‐adenosylmethionine to form phylloquinol. The site of the prenylation reaction is the chloroplast envelope membrane.