The HLA Antigens of Two Negrito Populations in the Philippines

Abstract
HLA antigens were determined for the A, B and C loci among 86 Aetas of west‐central Luzon and 87 Mamanwas of north‐eastern Mindanao, Philippines. The overall antigenic profiles of these two groups were essentially similar to those of other Asian‐Pacific populations with some peculiarities in common with Papua New Guineans. However, the results of heterogeneity tests and the comparison of statistically significant phenotypic associations showed a highly significant difference between the Aeta and the Mamanwa groups. It was postulated that the two “Negrito” groups represent different migrations to the Philippines.

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