Localization of the heparin-releasable lipase in situ in the rat liver
- 1 July 1979
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 181 (1) , 245-246
- https://doi.org/10.1042/bj1810245
Abstract
Immunofluorescence and immuno-electron microscopy were used for the localization of the heparin-releasable lipase in situ in the rat liver. The lipase is located exclusively on the liver endothelial cells. No labelling could be detected on the parenchymal of Kupffer cells, or in the livers of heparin-pretreated animals. The physiological significance of the endothelial localization of the hepatic lipase is discussed.This publication has 15 references indexed in Scilit:
- A simple purification procedure for rat hepatic lipaseFEBS Letters, 1979
- Binding of liver lipase to parenchymal and non-parenchymal rat liver cellsBiochemical and Biophysical Research Communications, 1978
- In vivo uptake of human and rat low density and high density lipoprotein by parenchymal and nonparenchymal cells from rat liverBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1978
- Hydrolysis of monoacylglycerol in lipoprotein remnants catalyzed by the liver plasma membrane monoacylglycerol acyltransferase.Journal of Biological Chemistry, 1978
- High density lipoprotein and low density lipoprotein catabolism by human liver and parenchymal and non-parenchymal cells from rat liverBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1977
- Rate constants for the uptake of cholesterol from various intestinal and serum lipoprotein fractions by the liver of the rat in vivoBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1977
- Metabolism of iodinated very low density lipoprotein in the rat: Autoradiographic localization in the liverBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1974
- Solubilization by Heparin of the Phospholipase A1 from the Plasma Membranes of Rat LiverJournal of Biological Chemistry, 1973
- Characterization, Subcellular Localization, and Partial Purification of a Heparin-released Triglyceride Lipase from Rat LiverJournal of Biological Chemistry, 1973
- Comparison of the triglyceride lipase of liver, adipose tissue, and postheparin plasmaJournal of Lipid Research, 1972