Primary structure of the site on bovine hormone‐sensitive lipase phosphorylated by cyclic AMP‐dependent protein kinase
Open Access
- 29 February 1988
- journal article
- Published by Wiley in FEBS Letters
- Vol. 229 (1) , 68-72
- https://doi.org/10.1016/0014-5793(88)80799-3
Abstract
The primary structure of a region on hormone‐sensitive lipase was determined to be: Lys‐Thr‐Glu‐Pro‐Met‐Arg‐Arg‐Ser‐Val‐Ser‐Glu‐Ala‐Ala‐Leu‐Thr‐Gln‐Pro‐Glu‐Gly‐Pro‐Leu‐Gly‐Thr‐Asp‐Ser‐Leu‐Lys. Ser‐8 was the only residue in the intact protein phosphorylated by cyclic AMP‐dependent protein kinase. However, Ser‐10 also appeared to be present in a phosphorylated form, suggesting that it is a target for a distinct protein kinase in vivo.Keywords
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