Human absorption of crude coal tar products
- 1 July 1984
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Dermatology
- Vol. 120 (7) , 874-877
- https://doi.org/10.1001/archderm.120.7.874
Abstract
• Five normal adult volunteers without cutaneous disease applied 2% crude coal tar to the skin for eight-hour periods on two consecutive days. Blood extracts subjected to gas chromatography and mass spectrometry yielded evidence of absorption in all five volunteers. Phenanthrene, anthracene, pyrene, and fluoranthene, found in four of our volunteers, have been shown to be tumor initiators or cocarcinogens. (Arch Dermatol1984;120:874-877)This publication has 1 reference indexed in Scilit:
- Mutagenicity of Urine from Psoriatic Patients Undergoing Treatment with Coal Tar and Ultraviolet LightJournal of Investigative Dermatology, 1981